Scientific References

Evidence-Based Relief

Multiple studies have shown that LDRT has benefits in the management of osteoarthritis and other benign soft tissue conditions, including pain reduction and functional improvement. Follow the links below to read the scientific literature on this treatment.

1. Osteoarthritis | Hoveidaei, Armin, Mehdi Karimi, Amirhossein Salmannezhad, Yasaman Tavakoli, Seyed Pouya Taghavi, and Amir Human Hoveidaei. “Low‑Dose Radiation Therapy (LDRT) in Managing Osteoarthritis: A Comprehensive Review.” Current Therapeutic Research, Clinical and Experimental, vol. 102, 12 Feb. 2025 https://www.sciencedirect.com/science/article/pii/S0011393X25000025

2. Osteoarthritis | Dove APH, Cmelak A, Darrow K, et al. The use of low-dose radiation therapy in osteoarthritis: a review. https://pubmed.ncbi.nlm.nih.gov/35504501/

3. Osteoarthritis | Kim BH, Bae HC, Wang SY, et al. Low-dose irradiation may mitigate osteoarthritis progression via anti-inflammatory mitochondrial modulation. https://pubmed.ncbi.nlm.nih.gov/35259418/

4. Osteoarthritis | Niewald M, Müller LN, Hautmann MG, et al. ArthroRad trial: randomized study of low-dose radiotherapy for osteoarthritis pain after 3 months. https://pubmed.ncbi.nlm.nih.gov/34724085/

5. Osteoarthritis | Rühle A, Tkotsch E, Mravlag R, et al. Low-dose radiotherapy for painful osteoarthritis in the elderly: multicenter analysis of 970 patients. https://pubmed.ncbi.nlm.nih.gov/34342662/

6. Osteoarthritis | Álvarez B, Montero A, Alonso R, et al. Low-dose radiation for hand osteoarthritis: shaking hands again? https://pubmed.ncbi.nlm.nih.gov/34585316/

7. Osteoarthritis | Canyilmaz E, Canyilmaz F, Aynaci O, et al. Radiotherapy vs. steroid injection for plantar fasciitis: a randomized trial.v https://pubmed.ncbi.nlm.nih.gov/25936814/

8. Osteoarthritis | Abdelmaqsoud A, Vorotniak N, Strauß D, Hentschel B. Analgesic effect of low-dose radiotherapy in benign musculoskeletal pain: a retrospective cohort study. https://www.cambridge.org/core/journals/journal-of-radiotherapy-in-practice/article/abs/analgesic-effect-of-lowdose-radiotherapy-in-treating-benign-musculoskeletal-painful-disorders-using-different-energies-a-retrospective-cohort-study/4360920C1E98DF09D012DAF879CBA4D9

9. Osteoarthritis | Weissmann T, Rückert M, Putz F, et al. Low-dose radiotherapy for osteoarthritis: biological mechanisms and clinical effects. https://pmc.ncbi.nlm.nih.gov/articles/PMC10674008/

10. Achilles tendonitis | Ott, Oliver J., et al. "Radiotherapy for benign achillodynia: long-term results of the Erlangen dose optimization trial." Strahlentherapie Und Onkologie 191.12 (2015): 979-984.
https://pubmed.ncbi.nlm.nih.gov/26369640/

11. Epicondylitis | Ott, O. J., et al. "Benign painful elbow syndrome: first results of a single center prospective randomized radiotherapy dose optimization trial." (2012): 873-877. https://pubmed.ncbi.nlm.nih.gov/22918610/

12. Rotator Cuff Tendonitis | Niewald, Marcus, et al. "Long-term results of radiotherapy for periarthritis of the shoulder: a retrospective evaluation." Radiation Oncology 2.1 (2007): 34. https://pmc.ncbi.nlm.nih.gov/articles/PMC2078592/